The Misuse of Muggle Artefacts Office regulated the use of magic on Muggle objects and tried to keep items that had been bewitched away from Muggles. To this end, members of the Office often participated in raids to keep Dark magic items out of circulation. There appeared to be a law prohibiting the enchantment of a Muggle item with the intent to use it for purposes other than what it was designed for.

Its purpose was to confiscate fake protective spells and charmed objects (such as cursed sneakscopes, or in one particular case, a medal that turned the user orange). It was unclear as to the purpose of making these devices, whether it be simply profiteering, or if it was something darker, as some of the confiscated articles were highly dangerous.

The Office is responsible for investigating offences under the Decree for the Reasonable Restriction of Underage Sorcery and the International Confederation of Wizards Statute of Secrecy. The Decree prohibits an underage wizard or witch from performing magic, while the Statute of Secrecy prohibits wizards and witches from performing magic in the presence of Muggles or in a Muggle-inhabited area.